Ctrl+R can't be used, it's already in use for "remove from the list", I think it's not a good shortcut for this either, Ctrl+R is using to refresh view, so the user may remove one or more items from the list by mistake, while he try to refresh view.
When you are using default settings often, you can use the option in menu > Options > Start with empty settings, or you can save the profile with default settings and option "Activate Profiles combo box first".
F5 is the basic hotkey in all dual-panel file managers to copy item(s) to other panel, it's much better and faster than Ctrl+C, Tab, Ctrl+V, Tab, you can use option to auto-minimize dialog, use the queue, so u can copy files just using a single hotkey, but it's OT.